FOR RESEARCH USE ONLY  •  NOT FDA APPROVED  •  MUST BE 21+  •  RESEARCH PURPOSES ONLY

GHK-Cu 100mg

GHK-Cu is a naturally occurring copper-binding tripeptide consisting of the amino acid sequence glycine-histidine-lysine (Gly-His-Lys) coordinated to a copper(II) ion. Its molecular formula is C14H21CuN6O4, molecular weight 404.9 g/mol, and CAS registry number 89030-95-5. In purified form, the compound presents as a blue crystalline powder — a visual property that arises directly from the chelated copper center, which absorbs light in the orange-red wavelengths. GHK-Cu was first characterized in 1973 by researcher Loren Pickart while studying biological activity differences between plasma samples from donors of varying ages. His initial observations noted that plasma from younger individuals retained a greater capacity to support certain hepatic cell functions, and subsequent fractionation identified this copper-tripeptide complex as the key differentiating factor. GHK-Cu is endogenously present in human plasma, saliva, and urine at trace concentrations, and circulating levels appear to change across the lifespan. The copper ion in GHK-Cu is coordinated through the nitrogen atoms of the glycine amino terminus and the imidazole ring of the histidine residue, forming a stable square-planar complex. This metal-peptide coordination places GHK-Cu in a relatively unusual structural category among short peptides. The chelated copper(II) center gives the compound distinct physicochemical behavior compared to the uncomplexed tripeptide Gly-His-Lys, including high water solubility, a characteristic absorption spectrum in the visible range, and improved stability under standard laboratory conditions. Published research involving GHK-Cu spans multiple scientific disciplines, including dermatology, wound biology, extracellular matrix biology, and aging research. Peer-reviewed studies have examined the compound's interactions with dermal fibroblasts, collagen-remodeling enzymes, antioxidant gene networks, and various cell surface receptors in cell-culture systems. This compound is supplied as a lyophilized powder for laboratory research use only by qualified professionals. It is not intended for human or veterinary use, nor for use in clinical diagnostic or therapeutic applications.

$75.00

GHK-Cu is a naturally occurring copper-binding tripeptide consisting of the amino acid sequence glycine-histidine-lysine (Gly-His-Lys) coordinated to a copper(II) ion.

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For laboratory research purposes only by qualified professionals. This product has not been evaluated by the FDA for clinical application.

  US-Based Company
  • ✓ 99.73% Purity — Third-Party COA Verified
  • ✓ CAS: 89030-95-5
  • ✓ Lyophilized powder, research grade
  • ✓ For laboratory research use by qualified professionals
Batch Verified
USA Lab Tested
Ships from Las Vegas, NV
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Certificate of Analysis

Every ITide Labs batch is verified by independent third-party laboratory analysis for purity and identity before release.

Endo Passed
99.73%
Purity
Lot #1
Batch
May 2026
Tested
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Overview

GHK-Cu is a naturally occurring copper-binding tripeptide consisting of the amino acid sequence glycine-histidine-lysine (Gly-His-Lys) coordinated to a copper(II) ion. Its molecular formula is C14H21CuN6O4, molecular weight 404.9 g/mol, and CAS registry number 89030-95-5. In purified form, the compound presents as a blue crystalline powder — a visual property that arises directly from the chelated copper center, which absorbs light in the orange-red wavelengths.

GHK-Cu was first characterized in 1973 by researcher Loren Pickart while studying biological activity differences between plasma samples from donors of varying ages. His initial observations noted that plasma from younger individuals retained a greater capacity to support certain hepatic cell functions, and subsequent fractionation identified this copper-tripeptide complex as the key differentiating factor. GHK-Cu is endogenously present in human plasma, saliva, and urine at trace concentrations, and circulating levels appear to change across the lifespan.

The copper ion in GHK-Cu is coordinated through the nitrogen atoms of the glycine amino terminus and the imidazole ring of the histidine residue, forming a stable square-planar complex. This metal-peptide coordination places GHK-Cu in a relatively unusual structural category among short peptides. The chelated copper(II) center gives the compound distinct physicochemical behavior compared to the uncomplexed tripeptide Gly-His-Lys, including high water solubility, a characteristic absorption spectrum in the visible range, and improved stability under standard laboratory conditions.

Published research involving GHK-Cu spans multiple scientific disciplines, including dermatology, wound biology, extracellular matrix biology, and aging research. Peer-reviewed studies have examined the compound's interactions with dermal fibroblasts, collagen-remodeling enzymes, antioxidant gene networks, and various cell surface receptors in cell-culture systems. This compound is supplied as a lyophilized powder for laboratory research use only by qualified professionals. It is not intended for human or veterinary use, nor for use in clinical diagnostic or therapeutic applications.

For laboratory research purposes only by qualified professionals. This product has not been evaluated by the FDA for clinical application.

Key Characteristics
Molecular Profile
FormulaC14H24CuN6O4
Mol. Weight403.92
CAS89030-95-5
Physical Properties
FormLyophilized blue crystalline powder
SolubilityHighly water-soluble
Natural SourcePresent in human plasma, saliva, and urine
StorageRefrigerate at 2–8°C (36–46°F)
StabilityProtect from light and moisture

For laboratory research purposes only by qualified professionals. This product has not been evaluated by the FDA for clinical application.

Additional information

Weight 0.1 lbs
Dimensions 12 × 15 × 0.5 in
Size

100mg

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